"About 6 million women in the United States use hormone replacement therapy to treat symptoms of menopause," Salman Hyder, the endowed professorship Zalk angiogenesis volume and professor of biomedical sciences at the University of Missouri College of Veterinary Medicine and Dalton Cardiovascular Research Center , said in a statement to the media. "This exposure to progestin would predispose a large number of postmenopausal women for the future development of breast cancer. The results of the study show that women could potentially take curcumin to protect them from developing progestin-accelerated tumors."
For their study, which has been accepted for future publication in the Journal of menopause, the research team found that curcumin delayed the onset of progestin-accelerated tumors in laboratory experiments on animals. The spice also decreased the incidence and reduce the number of progestin-fuels breast tumors in animal studies. In fact, curcumin prevented the appearance of gross morphological abnormalities in animals »mammary glands.
In previous studies, University of Missouri researchers have shown that progestin caused the rapid growth of certain tumors because it increases the hormone production of vascular endothelial growth factor (VEGF). This is known as VEGF to spur blood supply to cancerous tumors, making them grow faster. Hyder explained to the media statement that curcumin has been found to inhibit progestin-induced secretion of VEGF from the cells of breast cancer. Thus, inhibiting the production of VEGF, the proliferation of cells of breast cancer should be reduced
"Curcumin and other potential anti-angiogenic compounds to be tested further as a dietary chemopreventive agents in women already exposed to hormone replacement therapy containing estrogen and progestin, in an attempt to reduce or delay the risk of breast cancer associated with combined therapy hormone replacement therapy, "Hyder eipomenos
According to the American Cancer Society, which combines the use of estrogen with progestin HRT for several years not only increases the risk of developing breast cancer but the chances of dying from the disease. HRT contains two hormones make breasts more dense and increases the risk of cancer may be found in more advanced stag
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